Packers vs Rams Prediction, Odds, Spreads, Injuries, Trends for NFL Week 5

The Green Bay Packers are 2-2 this season – but 0-2 when Jordan Love starts – heading into Week 5 against the struggling Los Angeles Rams.

Cooper Kupp and Puka Nacua won’t be playing for the Rams in Week 5, leaving Matthew Stafford to work hard to lead his team to a 2-3 start.

On the Green Bay side, Love is back and healthy and had a strong second half in the loss to Minnesota in Week 5 – even if it wasn’t enough.

Can the Packers bounce back as away favorites?

Here’s a breakdown of the odds, the key players to watch, and my best bet for when two playoff teams from last season meet on Sunday.

Odds via FanDuel Sportsbook.

Spread

Money line

In total

Packers injury report

Rams injury report

Green Bay Packers

Jordan Love: The star quarterback missed two games with an MCL injury and struggled in the first half against Minnesota. But he bounced back and threw for four scores and 389 yards — but he also threw three picks. Los Angeles has a weaker defense than Minnesota, which should help Love get back on track.

Los Angeles Rams

Kyren Williams: Los Angeles doesn’t have many healthy weapons right now, but Kyren Williams is on the rise. The running back had three scores in Week 3 and then ran for 94 yards and a score on 19 carries in Week 4. He should have a heavy workload against the Pack.

My favorite play in this game is the Packers overall – as the Rams were terrible defensively in the 2024 season.

Los Angeles has allowed the second-most points (115) in the league, ahead of only the Carolina Panthers. The Rams rank last in yards per game and have allowed the fourth-most yards per carry in the league.

This is a perfect matchup for a Green Bay offense that has scored 25.5 points in three of four games and scored 29 points in both of Love’s starts.

Love threw for 389 yards and four scores in Week 4, and I expect him to play even better with another week of rehab for his knee.

Since Green Bay’s offense is relatively healthy and talented in the passing and running games, I think they could score 30 or more points in Week 5.

Pick: Packers OVER 25.5 points (-118)

Odds are updated regularly and are subject to change.

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